Terahertz pulsed imaging of knee cartilage
نویسندگان
چکیده
Osteoarthritis (OA) is a common form of arthritis caused by cartilage degeneration. In this paper, we investigate the potential use of terahertz (THz) pulsed imaging to quantitatively measure the early symptoms of OA in an animal model. THz images of excised rabbit femoral condyles were taken. We observe THz waves reflected off different layers within samples and demonstrate that the optical delay between reflections can give a quantitative measure of the thicknesses of particular tissues within cartilage.
منابع مشابه
Detection and identification of explosives using terahertz pulsed spectroscopic imaging
The absorption spectrum of the explosive 1,3,5-trinitro-1,3,5-triazacyclohexane sRDXd has been measured using a conventional Fourier transform infrared spectroscopy and by terahertz pulsed spectroscopy. Seven absorption features in the spectral range of 5–120 cm−1 have been observed and identified as the fingerprint of RDX. Furthermore, the spatial distribution of individual chemical substances...
متن کامل3D Chemical mapping using terahertz pulsed imaging
We report the use of a terahertz pulsed imaging technique for three-dimensional chemical mapping. Terahertz radiation reflected from a sample was measured pixel-by-pixel in time domain using a terahertz pulsed imaging system developed at TeraView Ltd, UK. The recorded terahertz waveforms were then transformed into frequency domain using time-partitioned Fourier transform. Structural maps of sam...
متن کاملقابلیت MRI در بررسی آسیب های غضروف مفصلی در بیماران مبتلا به استئوآرتریت مفصل زانو: مروری نظام مند بر مطالعات گذشته
Background and purpose: Osteoarthritis is a common degenerative joint disease affecting the synovial joints. Cartilage lesion is an important disorder at different degrees associated with osteoarthritis. The purpose of this systematic review was to determine whether magnetic resonance imaging (MRI) is a valid and reliable tool to detect the articular cartilage lesions in patients with knee oste...
متن کاملIs there any Role for Pulsed Electromagnetic Fields in the Treatment of Early Osteoarthritis of the Knee?
Objective: Pulsed Electromagnetic Fields (PEMFs) were introduced in the clinical setting in the 1970s. Proven to be a successful method of treating non-union and delayed union of fractures, its effects on cartilage has remained ambiguous. PEMFs have demonstrated a pro-anabolic and anti-catabolic activity on cartilage metabolism. We hypothesized that the use of PEMFs in patients with symptomatic...
متن کاملIn-Vitro Evaluation of Pre- and Post-Compression States of Human Articular Cartilage Using MRI at 3 Tesla
The purpose of this study was to evaluate changes of several MR parameters (T1, T2 and ADC) before and after compression in human cartilage samples using unique microimaging compression system. Cartilage samples were prepared from joints of 10 patients, who underwent a total knee joint replacement. Study was performed on a Bruker 3T Medspec whole-body scanner (Bruker, Ettlingen, Germany) using ...
متن کامل